Retatrutide
Triple GIP / GLP-1 / glucagon agonist
2 → 4 → 6 → 9 → 12 mg · 4-week steps
Highest studied dose: 12 mg/week
SourceJastreboff AM et al., NEJM 2023 (phase 2) · Giblin MJ et al., Diabetes Obesity and Metabolism 2026 (TRIUMPH design) · Eli Lilly, TRIUMPH-1 topline results, 21 May 2026
Not approved in any country to date — schedule taken from a clinical trial protocol.
